InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271) (CF879010)

Name: InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271)
Brand: abinScience
SKU: CF879010
Price: 370 USD
Availability: InStock

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Precio(USD):

Especificación:

100ug
1mg

Número:

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Referencias
Datasheet
SDS

Vista general

Número de catálogo	CF879010
Descripción	InVivoMAb Anti-Dog TNFa/TNF-alpha Antibody (Iv0271) [Iv0271] (CF879010) is a dog monoclonal antibody detecting TNF in Blocking, ELISA, FCM. Suitable for Dog. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Reactividad de especies	Canine
Aplicaciones	Blocking, ELISA, FCM
Especie huésped	Canine
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	Iv0271
Objetivo	C-domain 1, C-domain 2, Cachectin, ICD1, ICD2, Intracellular domain 1, Intracellular domain 2, N-terminal fragment, NTF, TNF, TNF-a, TNF-alpha, TNFA, TNFSF2, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, Tumor necrosis factor, soluble form
Nivel de endotoxinas	< 1 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Productos asociados	pH 7.4 Dilution Buffer
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P51742
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Tumor necrosis factor (TNFa/TNF-alpha) is a ~25 kDa protein. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. TNFa is the therapeutic target of adalimumab (Humira).
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Dog TNFa/TNF-alpha Antibody (Iv0271)
Bioactivity

Detects recombinant dog TNFa/TNF-alpha (Catalog No: CF879011) in indirect ELISA

Referencias

Datasheet

InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271).pdf

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Formula

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