InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271) (CF879010)

Name: InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271)
Brand: abinScience
SKU: CF879010
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

Количество:

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Обзор

Каталожный номер	CF879010
Описание	InVivoMAb Anti-Dog TNFa/TNF-alpha Antibody (Iv0271) [Iv0271] (CF879010) is a dog monoclonal antibody detecting TNF in Blocking, ELISA, FCM. Suitable for Dog. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Реактивность видов	Canine
Применения	Blocking, ELISA, FCM
Хозяинский вид	Canine
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	Iv0271
Цель	C-domain 1, C-domain 2, Cachectin, ICD1, ICD2, Intracellular domain 1, Intracellular domain 2, N-terminal fragment, NTF, TNF, TNF-a, TNF-alpha, TNFA, TNFSF2, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, Tumor necrosis factor, soluble form
Уровень эндотоксинов	< 1 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Связанные продукты	pH 7.4 Dilution Buffer
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P51742
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Tumor necrosis factor (TNFa/TNF-alpha) is a ~25 kDa protein. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. TNFa is the therapeutic target of adalimumab (Humira).
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Dog TNFa/TNF-alpha Antibody (Iv0271)
Bioactivity

Detects recombinant dog TNFa/TNF-alpha (Catalog No: CF879011) in indirect ELISA

Ссылки

Даташит

InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271).pdf

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