

| Número de catálogo | VK646020 | ||||
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| Descripción |
InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260) [Iv0260] (VK646020) is a human monoclonal antibody detecting Envelopment polyprotein in ELISA, Neutralization. Suitable for Seoul virus (SEOV) and Andes virus (ANDV).
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| Reactividad de especies | Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV), Orthohantavirus puumalaense (Puumala virus) (PUUV), Dobrava-Belgrade virus (DOBV), Seoul virus (SEOV), Andes virus (Andes orthohantavirus), Sin Nombre virus (SNV) | ||||
| Aplicaciones | ELISA, Neutralization | ||||
| Especie huésped | Human | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1 | ||||
| ID de clon | Iv0260 | ||||
| Objetivo | Envelopment polyprotein, M polyprotein, Glycoprotein C, Gc, Glycoprotein G2, GP | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Productos asociados | pH 7.4 Dilution Buffer | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q89905 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Envelopment polyprotein (Glycoprotein C/Gc) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif. | ||||
| Nota | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260)




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