InVivoMAb Anti-Hantavirus Glycoprotein Gc Broad-Neutralizing Antibody (Iv0260) (VK646020)

Name: InVivoMAb Anti-Hantavirus Glycoprotein Gc Broad-Neutralizing Antibody (Iv0260)
Brand: abinScience
SKU: VK646020
Price: 370 USD
Availability: InStock

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Prix(USD) :

Spécification :

100ug
1mg

Nombre :

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK646020

Description

InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260) [Iv0260] (VK646020) is a human monoclonal antibody detecting Envelopment polyprotein in ELISA, Neutralization. Suitable for Seoul virus (SEOV) and Andes virus (ANDV).

Reactivité des espèces

Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV), Orthohantavirus puumalaense (Puumala virus) (PUUV), Dobrava-Belgrade virus (DOBV), Seoul virus (SEOV), Andes virus (Andes orthohantavirus), Sin Nombre virus (SNV)

Applications

ELISA, Neutralization

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG1

ID de clone

Iv0260

Cible

Envelopment polyprotein, M polyprotein, Glycoprotein C, Gc, Glycoprotein G2, GP

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Produits associés

pH 7.4 Dilution Buffer

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q89905

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Envelopment polyprotein (Glycoprotein C/Gc) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif.

Note

For research use only. Not suitable for clinical or therapeutic use.

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