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| カタログ番号 | VK562030 |
|---|---|
| 説明 |
InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12) [3G12] (VK562030) is a human monoclonal antibody detecting Major surface glycoprotein G in ELISA, Neutralization, WB.
Highlights
|
| 種反応性 | Human respiratory syncytial virus A (HRSV-A) |
| アプリケーション | ELISA, Neutralization, WB |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | 3G12 |
| ターゲット | Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, Mature secreted glycoprotein G, Mature sG, G |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P03423 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Major surface glycoprotein G is a ~32 kDa protein. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable). 1. Feldman, SA. et al. (1999) Journal of virology 73, 6610-7. PMID: 10400758 2. Feldman, SA. et al. (2000) Journal of virology 74, 6442-7. PMID: 10864656 3. Levine, S. et al. (1987) The Journal of general virology 68 ( Pt 9), 2521-4. PMID: 3655746 4. Tripp, RA. et al. (2001) Nature immunology 2, 732-8. PMID: 11477410 5. Jeong, KI. et al. (2015) PloS one 10, e0130517. PMID: 26107373 6. Johnson, SM. et al. (2015) PLoS pathogens 11, e1005318. PMID: 26658574 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12)
Detects recombinant HRSV G/Major surface glycoprotein G (Catalog No: VK562011) in indirect ELISA
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中国武漢市深敦寺路666号C棟、武漢、430206
