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InVivoMAb Anti-Human CRACC/SLAMF7 Antibody (Iv0264) (HV217010)

InVivoMAb Anti-Human CRACC/SLAMF7 Antibody (Iv0264)
InVivoMAb Anti-Human CRACC/SLAMF7 Antibody (Iv0264)
Precio(USD):
Especificación:
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoHV217010
Descripción
InVivoMAb Anti-Human CD319/SLAMF7 Antibody (Iv0264) [Iv0264] (HV217010) is a human monoclonal antibody detecting SLAMF7 in ELISA, Neutralization, WB. Suitable for Human.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, Neutralization, WB
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonIv0264
Objetivo SLAMF7, CRACC, Protein 19A, SLAM family member 7, CD2-like receptor-activating cytotoxic cells, Membrane protein FOAP-12, CD319, Novel Ly9, CD2 subset 1, CS1
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9NQ25
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

SLAM family member 7 (CD319/SLAMF7) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B.

1. Bouchon, A. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 5517-21. PMID: 11698418
2. Tassi, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7996-8002. PMID: 16339536
3. Murphy, JJ. et al. (2002) The Biochemical journal 361, 431-6. PMID: 11802771
4. Kim, JR. et al. (2013) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 62, 765-72. PMID: 23695528
Nota For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)
Imágenes
  • InVivoMAb Anti-Human CRACC/SLAMF7 Antibody (Iv0264)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Human CD319/SLAMF7 Antibody (Iv0264)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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