InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136) (HB782010)

Name: InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136)
Brand: abinScience
SKU: HB782010
Price: 370 USD
Availability: InStock

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Цена(USD):

Спецификация:

100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HB782010

Описание

InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136) [Iv0136] (HB782010) is a human monoclonal antibody detecting Tumor necrosis factor receptor superfamily member 5 in ELISA, Neutralization. Suitable for Human.

Реактивность видов

Human

Применения

ELISA, Neutralization, FCM

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG1, kappa

ID клона

Iv0136

Проверенные приложения

FCM

Цель

B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5

Уровень эндотоксинов

< 1 EU/mg

Чистота

>95% as determined by SDS-PAGE.

Связанные продукты

pH 7.4 Dilution Buffer

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P25942

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4.

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Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973

Примечание

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

Bioactivity

Detects CD40/TNFRSF5 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136).
Flow CytoMetry

Flow-cytometry using APC anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD40 monoclonal antibody (Catalog: HB782010, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using FITC anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD40 monoclonal antibody (Catalog: HB782010, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.