InVivoMAb Anti-Human E-Cadherin/Cadherin-11 Antibody (23C6) (HY460010)

Name: InVivoMAb Anti-Human E-Cadherin/Cadherin-11 Antibody (23C6)
Brand: abinScience
SKU: HY460010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Aperçu

Numéro de catalogue	HY460010
Description	InVivoMAb Anti-Human CDH1/CDH11 Antibody (23C6) [23C6] (HY460010) is a mouse monoclonal antibody detecting CD324 in ELISA, FCM, Neutralization. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Reactivité des espèces	Human
Applications	ELISA, FCM, Neutralization
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	23C6
Cible	CD324, Uvomorulin, Epithelial cadherin, E-cadherin, CDHE, CAM 120/80, UVO, CDH1, Cadherin-1, CDH11, OSF-4, Osteoblast cadherin, Cadherin-11, OB-cadherin
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Produits associés	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P12830, P55287
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Cadherin-1 (CDH1/CDH11) is a ~97 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Promotes organization of radial actin fiber structure and cellular response to contractile forces, via its interaction with AMOTL2 which facilitates anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane. Plays a role in the early stages of desmosome cell-cell junction formation via facilitating the recruitment of DSG2 and DSP to desmosome plaques. 1. Meigs, TE. et al. (2002) The Journal of biological chemistry 277, 24594-600. PMID: 11976333 2. Shafraz, O. et al. (2018) eLife 7. PMID: 29999492
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for InVivoMAb Anti-Human CDH1/CDH11 Antibody (23C6)

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InVivoMAb Anti-Human E-Cadherin/Cadherin-11 Antibody (23C6).pdf

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