InVivoMAb Anti-Human ErbB3/Her3 Antibody (Iv0184) (HB116010)

Name: InVivoMAb Anti-Human ErbB3/Her3 Antibody (Iv0184)
Brand: abinScience
SKU: HB116010
Price: 370 USD
Availability: InStock

データシート製品共有情報コピー

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100ug
1mg

数量:

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HB116010
説明	InVivoMAb Anti-Human ERBB3/HER3 Antibody (Iv0184) [Iv0184] (HB116010) is a human monoclonal antibody detecting ERBB3 in ELISA. Suitable for Human.
種反応性	Human
アプリケーション	ELISA
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	Iv0184
ターゲット	ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
関連製品	pH 7.4 Dilution Buffer
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P21860
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Receptor tyrosine-protein kinase erbB-3 (ERBB3/HER3) is a ~148 kDa protein. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. 1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 2. Kinugasa, Y. et al. (2004) Biochemical and biophysical research communications 321, 1045-9. PMID: 15358134 3. Braunstein, EM. et al. (2016) Leukemia 30, 2242-2245. PMID: 27416908
注意事項	For research use only. Not suitable for clinical or therapeutic use.