InVivoMAb Anti-Human FCRN/FCGRT Antibody (Iv0203) (HX061010)

Name: InVivoMAb Anti-Human FCRN/FCGRT Antibody (Iv0203)
Brand: abinScience
SKU: HX061010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Número de catálogo	HX061010
Descripción	InVivoMAb Anti-Human FCGRT/FCRN Antibody (Iv0203) [Iv0203] (HX061010) is a mouse monoclonal antibody detecting IgG Fc fragment receptor transporter alpha chain in ELISA, Neutralization. Suitable for Human.
Reactividad de especies	Human
Aplicaciones	ELISA, Neutralization
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	Iv0203
Objetivo	IgG Fc fragment receptor transporter alpha chain, IgG receptor FcRn large subunit p51, FcRn, FCGRT, FCRN, Neonatal Fc receptor
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Productos asociados	pH 7.4 Dilution Buffer
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P55899
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	IgG receptor FcRn large subunit p51 (FCGRT) is a ~39 kDa protein. Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. 1. West, AP. et al. (2000) Biochemistry 39, 9698-708. PMID: 10933786 2. Story, CM. et al. (1994) The Journal of experimental medicine 180, 2377-81. PMID: 7964511 3. Mikulska, JE. et al. (2000) European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 27, 231-40. PMID: 10998088 4. Oganesyan, V. et al. (2014) The Journal of biological chemistry 289, 7812-24. PMID: 24469444 5. Pyzik, M. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E2862-E2871. PMID: 28330995
Nota	For research use only. Not suitable for clinical or therapeutic use.