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InVivoMAb Anti-LASV GPC Antibody (LAVA01) (VK453010)

InVivoMAb Anti-LASV GPC Antibody (LAVA01)
InVivoMAb Anti-LASV GPC Antibody (LAVA01)
Prix(USD) :
Spécification :
  • 100ug
  • 1mg
Nombre :
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  • Reférences

  • Fiche technique

  • SDS

Aperçu
Numéro de catalogueVK453010
Description
InVivoMAb Anti-LASV GPC Antibody (LAVA01) [LAVA01] (VK453010) is a human monoclonal antibody detecting Pre-glycoprotein polyprotein GP complex in ELISA, Neutralization.
Reactivité des espècesLassa virus (LASV)
ApplicationsELISA, Neutralization
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneLAVA01
Cible Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC, GP-C
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Produits associés pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P08669
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332
2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-LASV GPC Antibody (LAVA01)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-LASV GPC Antibody (LAVA01)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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