InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12) (MV029010)

Name: InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12)
Brand: abinScience
SKU: MV029010
Price: 370 USD
Availability: InStock

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Precio(USD):

Especificación:

100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MV029010

Descripción

InVivoMab Anti-Mouse CD366/HAVCR2/TIM-3 Antibody (B8.2C12) [B8.2C12] (MV029010) is a rat monoclonal antibody detecting CD366 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

Reactividad de especies

Mouse

Aplicaciones

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

Especie huésped

Rat

Clonalidad

Monoclonal

Isotipo

IgG1, kappa

ID de clon

B8.2C12

Objetivo

CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3

Nivel de endotoxinas

< 1 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q3KP82

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Hepatitis A virus cellular receptor 2 homolog (CD366/HAVCR2) is a ~30 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

1. Anderson, AC. et al. (2007) Science (New York, N.Y.) 318, 1141-3. PMID: 18006747

2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861

3. Sabatos, CA. et al. (2003) Nature immunology 4, 1102-10. PMID: 14556006

4. Lee, J. et al. (2011) Molecular and cellular biology 31, 3963-74. PMID: 21807895

5. Rangachari, M. et al. (2012) Nature medicine 18, 1394-400. PMID: 22863785

6. Jayaraman, P. et al. (2010) The Journal of experimental medicine 207, 2343-54. PMID: 20937702

7. Gorman, JV. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 3133-42. PMID: 24567532

8. DeKruyff, RH. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 1918-30. PMID: 20083673

9. Nakayama, M. et al. (2009) Blood 113, 3821-30. PMID: 19224762

Nota

For research use only.

Imágenes

Referencias

Datasheet

InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo