InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12) (MV029010)

Name: InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12)
Brand: abinScience
SKU: MV029010
Price: 370 USD
Availability: InStock

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Prix(USD) :

Spécification :

100ug
1mg

Nombre :

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SDS

Aperçu

Numéro de catalogue

MV029010

Description

InVivoMab Anti-Mouse CD366/HAVCR2/TIM-3 Antibody (B8.2C12) [B8.2C12] (MV029010) is a rat monoclonal antibody detecting CD366 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Mouse

Applications

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

Espèce hôte

Rat

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

B8.2C12

Cible

CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3

Niveau d'endotoxines

< 1 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q3KP82

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Hepatitis A virus cellular receptor 2 homolog (CD366/HAVCR2) is a ~30 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

1. Anderson, AC. et al. (2007) Science (New York, N.Y.) 318, 1141-3. PMID: 18006747

2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861

3. Sabatos, CA. et al. (2003) Nature immunology 4, 1102-10. PMID: 14556006

4. Lee, J. et al. (2011) Molecular and cellular biology 31, 3963-74. PMID: 21807895

5. Rangachari, M. et al. (2012) Nature medicine 18, 1394-400. PMID: 22863785

6. Jayaraman, P. et al. (2010) The Journal of experimental medicine 207, 2343-54. PMID: 20937702

7. Gorman, JV. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 3133-42. PMID: 24567532

8. DeKruyff, RH. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 1918-30. PMID: 20083673

9. Nakayama, M. et al. (2009) Blood 113, 3821-30. PMID: 19224762

Note

For research use only.

Images

Reférences

Fiche technique

InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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