InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12) (MV029010)

Name: InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12)
Brand: abinScience
SKU: MV029010
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

Количество:

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Обзор
Изображения
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Даташит
SDS

Обзор

Каталожный номер

MV029010

Описание

InVivoMab Anti-Mouse CD366/HAVCR2/TIM-3 Antibody (B8.2C12) [B8.2C12] (MV029010) is a rat monoclonal antibody detecting CD366 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

Реактивность видов

Mouse

Применения

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

Хозяинский вид

Rat

Клоональность

Monoclonal

Изотип

IgG1, kappa

ID клона

B8.2C12

Цель

CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3

Уровень эндотоксинов

< 1 EU/mg

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q3KP82

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Hepatitis A virus cellular receptor 2 homolog (CD366/HAVCR2) is a ~30 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

1. Anderson, AC. et al. (2007) Science (New York, N.Y.) 318, 1141-3. PMID: 18006747

2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861

3. Sabatos, CA. et al. (2003) Nature immunology 4, 1102-10. PMID: 14556006

4. Lee, J. et al. (2011) Molecular and cellular biology 31, 3963-74. PMID: 21807895

5. Rangachari, M. et al. (2012) Nature medicine 18, 1394-400. PMID: 22863785

6. Jayaraman, P. et al. (2010) The Journal of experimental medicine 207, 2343-54. PMID: 20937702

7. Gorman, JV. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 3133-42. PMID: 24567532

8. DeKruyff, RH. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 1918-30. PMID: 20083673

9. Nakayama, M. et al. (2009) Blood 113, 3821-30. PMID: 19224762

Примечание

For research use only.

Изображения

Ссылки

Даташит

InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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