InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3) (MY328020)

Name: InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3)
Brand: abinScience
SKU: MY328020
Price: 370 USD
Availability: InStock

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Prix(USD) :

Spécification :

100ug
1mg

Nombre :

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MY328020

Description

InVivoMAb Anti-Mouse IL6 (MP5-20F3) [MP5-20F3] (MY328020) is a rat monoclonal antibody detecting Interleukin-6 in ELISA, FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Mouse

Applications

ELISA, FCM, Functional assay, Research in vivo

Espèce hôte

Rat

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

MP5-20F3

Cible

B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6

Niveau d'endotoxines

< 1 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P08505

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Interleukin-6 (IL6) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). IL6 is the therapeutic target of tocilizumab (Actemra).

Note

For research use only.

Isotype Control

Rat IgG1, kappa Recombinant Isotype Control Antibody (RTK2071) (RV080407)

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