

| Каталожный номер | MY328020 | ||||
|---|---|---|---|---|---|
| Описание |
InVivoMAb Anti-Mouse IL6 (MP5-20F3) [MP5-20F3] (MY328020) is a rat monoclonal antibody detecting Interleukin-6 in ELISA, FACS, Functional assay, Research in vivo. Suitable for Mouse.
Highlights
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| Реактивность видов | Mouse | ||||
| Применения | ELISA, FCM, Functional assay, Research in vivo | ||||
| Хозяинский вид | Rat | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG1, kappa | ||||
| ID клона | MP5-20F3 | ||||
| Цель | B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6 | ||||
| Уровень эндотоксинов | < 1 EU/mg | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P08505 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Interleukin-6 (IL6) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). IL6 is the therapeutic target of tocilizumab (Actemra). | ||||
| Примечание | For research use only. | ||||
| Isotype Control | Rat IgG1, kappa Recombinant Isotype Control Antibody (RTK2071) (RV080407) |

SDS-PAGE for InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3)




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