InVivoMAb Anti-Mouse B7-H4 Antibody (Iv0257) (MV721010)

Name: InVivoMAb Anti-Mouse B7-H4 Antibody (Iv0257)
Brand: abinScience
SKU: MV721010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Aperçu

Numéro de catalogue	MV721010
Description	InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257) [Iv0257] (MV721010) is a mouse monoclonal antibody detecting V-set domain containing T-cell activation inhibitor 1 in ELISA, FCM, Neutralization. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Reactivité des espèces	Mouse
Applications	ELISA, FCM, Neutralization
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	Iv0257
Applications testées	FCM
Cible	V-set domain containing T-cell activation inhibitor 1, B7 homolog 4, B7-H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, Vtcn1, B7h4
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Produits associés	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q7TSP5
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	V-set domain containing T-cell activation inhibitor 1 (VTCN1/B7-H4) is a ~30 kDa protein. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Flow CytoMetry

Flow-cytometry using anti-human VTCN1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human VTCN1 monoclonal antibody (Catalog: MV721010) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.

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