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InVivoMAb Anti-SARS-CoV-2 RBD Antibody (C135)
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (C135)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
Количество:
Свяжитесь с нами
  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерVK565140
Описание
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (C135) [C135] (VK565140) is a human monoclonal antibody detecting Spike glycoprotein in ELISA, Neutralization. Suitable for SARS-CoV-2.
Реактивность видовSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
ПримененияELISA, Neutralization
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1
ID клонаC135
Цель Spike glycoprotein, Spike, S glycoprotein, RBD
Уровень эндотоксинов < 1 EU/mg
Чистота >95% as determined by SDS-PAGE.
Связанные продукты pH 7.4 Dilution Buffer
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P0DTC2
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Spike glycoprotein (RBD) is a ~141 kDa protein. Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2. When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell membrane. When S2/S2' has not been cleaved, binding to the receptor results in internalization of the virus by endocytosis using host TFRC and GRM2 and leading to fusion of the virion membrane with the host endosomal membrane. Alternatively, may use NRP1/NRP2 and integrin as entry receptors.

1. Hoffmann, M. et al. (2020) Cell 181, 271-280.e8. PMID: 32142651
2. Walls, AC. et al. (2020) Cell 181, 281-292.e6. PMID: 32155444
3. Cao, W. et al. (2021) Biophysical journal 120, 1011-1019. PMID: 33607086
4. Takeda, M. (2022) Microbiology and immunology 66, 15-23. PMID: 34561887
5. Wrapp, D. et al. (2020) Science (New York, N.Y.) 367, 1260-1263. PMID: 32075877
6. Ou, X. et al. (2020) Nature communications 11, 1620. PMID: 32221306
7. Wang, J. et al. (2021) Cell discovery 7, 119. PMID: 34903715
8. Wang, X. et al. (2023) Journal of virology 97, e0161122. PMID: 36779763
9. Daly, JL. et al. (2020) Science (New York, N.Y.) 370, 861-865. PMID: 33082294
10. Cantuti-Castelvetri, L. et al. (2020) Science (New York, N.Y.) 370, 856-860. PMID: 33082293
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • InVivoMAb Anti-SARS-CoV-2 RBD Antibody (C135)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-SARS-CoV-2 RBD Antibody (C135)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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