

| Каталожный номер | HB805437 |
|---|---|
| Реактивность видов | Human |
| Применения | FCM |
| Хозяинский вид | Rabbit |
| Клоональность | Monoclonal |
| Изотип | IgG |
| ID клона | SAA0004 |
| Конъюгация | APC |
| Цель | CD11A, Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, CD11 antigen-like family member A, CD11a, ITGAL, Integrin alpha-L |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Связанные продукты | Rabbit IgG Recombinant Isotype Control Antibody (HyHEL-10), APC |
| Номер доступа | P20701 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Фон | Integrin alpha-L (CD11a/ITGAL) is a ~128 kDa protein. Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. 1. Hermand, P. et al. (2000) The Journal of biological chemistry 275, 26002-10. PMID: 10846180 2. Shimaoka, M. et al. (2003) Cell 112, 99-111. PMID: 12526797 3. de Fougerolles, AR. et al. (1991) The Journal of experimental medicine 174, 253-67. PMID: 1676048 4. Dustin, ML. et al. (1986) Journal of immunology (Baltimore, Md. : 1950) 137, 245-54. PMID: 3086451 5. Ostermann, G. et al. (2002) Nature immunology 3, 151-8. PMID: 11812992 6. Fraemohs, L. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6259-64. PMID: 15528364 7. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055 8. Barber, DF. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3653-9. PMID: 15356110 9. Lacouture, C. et al. (2024) Nature communications 15, 407. PMID: 38195629 10. Kristóf, E. et al. (2013) Apoptosis : an international journal on programmed cell death 18, 1235-51. PMID: 23775590 |
| Примечание | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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