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Human ABCG5 Recombinant Protein (N-His) (HD924012)

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Aperçu
Numéro de catalogueHD924012
Description
Recombinant Human ABCG5 Protein, N-His (HD924012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Système d'expressionE. coli
Numéro d'accèsQ9H222
Longueur de protéineHis36-Lys349
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspècesHomo sapiens (Human)
Nature Recombinant
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >90% as determined by SDS-PAGE.
Forme Lyophilized
Tampon de stockage Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsABCG5, ATP-binding cassette sub-family G member 5, EC:7.6.2.-, Sterolin-1
Contexte

ATP-binding cassette sub-family G member 5 is a ~72 kDa protein. ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity.

1. Lee, JY. et al. (2016) Nature 533, 561-4. PMID: 27144356
2. Berge, KE. et al. (2000) Science (New York, N.Y.) 290, 1771-5. PMID: 11099417
3. Lee, MH. et al. (2001) Nature genetics 27, 79-83. PMID: 11138003
4. Graf, GA. et al. (2004) The Journal of biological chemistry 279, 24881-8. PMID: 15054092
5. Wang, Z. et al. (2006) Biochemistry 45, 9929-39. PMID: 16893193
6. Johnson, BJ. et al. (2010) Biochemistry 49, 3403-11. PMID: 20210363
Note For research use only
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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