

| Numéro de catalogue | HD924012 |
|---|---|
| Description |
Recombinant Human ABCG5 Protein, N-His (HD924012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q9H222 |
| Longueur de protéine | His36-Lys349 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | ABCG5, ATP-binding cassette sub-family G member 5, EC:7.6.2.-, Sterolin-1 |
| Contexte | ATP-binding cassette sub-family G member 5 is a ~72 kDa protein. ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity. 1. Lee, JY. et al. (2016) Nature 533, 561-4. PMID: 27144356 2. Berge, KE. et al. (2000) Science (New York, N.Y.) 290, 1771-5. PMID: 11099417 3. Lee, MH. et al. (2001) Nature genetics 27, 79-83. PMID: 11138003 4. Graf, GA. et al. (2004) The Journal of biological chemistry 279, 24881-8. PMID: 15054092 5. Wang, Z. et al. (2006) Biochemistry 45, 9929-39. PMID: 16893193 6. Johnson, BJ. et al. (2010) Biochemistry 49, 3403-11. PMID: 20210363 |
| Note | For research use only |
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