

| Каталожный номер | HD924012 |
|---|---|
| Описание |
Recombinant Human ABCG5 Protein, N-His (HD924012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q9H222 |
| Длина белка | His36-Lys349 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | ABCG5, ATP-binding cassette sub-family G member 5, EC:7.6.2.-, Sterolin-1 |
| Фон | ATP-binding cassette sub-family G member 5 is a ~72 kDa protein. ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity. 1. Lee, JY. et al. (2016) Nature 533, 561-4. PMID: 27144356 2. Berge, KE. et al. (2000) Science (New York, N.Y.) 290, 1771-5. PMID: 11099417 3. Lee, MH. et al. (2001) Nature genetics 27, 79-83. PMID: 11138003 4. Graf, GA. et al. (2004) The Journal of biological chemistry 279, 24881-8. PMID: 15054092 5. Wang, Z. et al. (2006) Biochemistry 45, 9929-39. PMID: 16893193 6. Johnson, BJ. et al. (2010) Biochemistry 49, 3403-11. PMID: 20210363 |
| Примечание | For research use only |
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