Human ADA Recombinant Protein (N-His) (HF562032)

Name: Human ADA Recombinant Protein (N-His)
Brand: abinScience
SKU: HF562032
Price: 211 USD
Availability: InStock

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Número de catálogo	HF562032
Descripción	Recombinant Human ADA Protein, N-His (HF562032) expressed in E. coli, spanning Thr57-Leu363. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P00813
Longitud de proteína	Thr57-Leu363
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	36.92 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ADA, ADA1, Adenosine aminohydrolase, Adenosine deaminase, EC:3.5.4.4
Fondo	Adenosine deaminase is a ~40 kDa protein. Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. 1. Eltzschig, HK. et al. (2006) Blood 108, 1602-10. PMID: 16670267 2. Gracia, E. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 1048-61. PMID: 23193172 3. Fattahi, A. et al. (2015) Urology 86, 730-4. PMID: 26166670 4. Lindley, ER. et al. (1993) The Biochemical journal 290 ( Pt 2), 457-62. PMID: 8452534 5. Jiang, C. et al. (1997) Human molecular genetics 6, 2271-8. PMID: 9361033 6. Martinez-Navio, JM. et al. (2011) Journal of leukocyte biology 89, 127-36. PMID: 20959412 7. Ginés, S. et al. (2002) The Biochemical journal 361, 203-9. PMID: 11772392 8. Gonzalez-Gronow, M. et al. (2004) The Journal of biological chemistry 279, 20993-8. PMID: 15016824 10. Li, G. et al. (2015) Pharmacology research & perspectives 3, e00121. PMID: 26038697
Nota	For research use only

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Datasheet

Human ADA Recombinant Protein (N-His).pdf

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