Human ADGRF1 Recombinant Protein (N-His) (HD298012)

Name: Human ADGRF1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD298012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HD298012
Description	Recombinant Human ADGRF1 Protein, N-His (HD298012) expressed in E. coli, spanning Thr298-Pro575. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q5T601
Longueur de protéine	Thr298-Pro575
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	32.95 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ADGRF1, ADGRF1 C-terminal fragment, ADGRF1 N-terminal fragment, Adhesion G-protein coupled receptor F1, Adhesion G-protein coupled receptor F1, C-terminal fragment, Adhesion G-protein coupled receptor F1, N-terminal fragment, G protein-coupled receptor 110, G protein-coupled receptor KPG_012, GPR110, PGR19
Contexte	Adhesion G-protein coupled receptor F1 is a ~101 kDa protein. Adhesion G-protein coupled receptor (aGPCR) for N-docosahexaenoylethanolamine (synaptamide), an omega-3 fatty acid lipid highly enriched in the brain. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRF1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Also able to couple to G(q), G(i) and G(12)/G(13) G proteins; additional evidence is however required to confirm this result in vivo. Involved in the development of neurons and cognitive function. 1. Lee, JW. et al. (2016) Nature communications 7, 13123. PMID: 27759003 2. Huang, BX. et al. (2020) Communications biology 3, 109. PMID: 32144388 3. Qu, X. et al. (2022) Nature 604, 779-785. PMID: 35418679 4. Zhu, X. et al. (2022) Nature communications 13, 5513. PMID: 36127364 5. Jones, DTD. et al. (2023) Nature communications 14, 2490. PMID: 37120430
Note	For research use only

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Human ADGRF1 Recombinant Protein (N-His).pdf

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