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Human AGRP Recombinant Protein (C-Fc) (HT100011)

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  • 1mg
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Aperçu
Numéro de catalogueHT100011
Description
Recombinant Human AGRP Protein, C-Fc (HT100011) expressed in Mammalian Cells, spanning Met1-Thr132. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expressionMammalian cells
Numéro d'accèsO00253
Longueur de protéineMet1-Thr132
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspècesHomo sapiens (Human)
Nature Recombinant
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >90% as determined by SDS-PAGE.
Masse moléculaire prédite 40.84 kDa
Forme Lyophilized
Tampon de stockage Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsAGRP, AGRT, ART, Agouti-related protein
Contexte

Agouti-related protein is a ~14 kDa protein. Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptors MC3R and MC4R by precluding agonist-induced signaling, thereby inhibiting cAMP production within the hypothalamus and adrenal gland. Involved in the control of feeding behavior via the central melanocortin system. Has very low activity towards MC5R. Also promotes endocytosis of MC3R and MC4R in an arrestin-dependent mechanism.

1. Bolin, KA. et al. (1999) FEBS letters 451, 125-31. PMID: 10371151
2. Nijenhuis, WA. et al. (2001) Molecular endocrinology (Baltimore, Md.) 15, 164-71. PMID: 11145747
3. Ollmann, MM. et al. (1997) Science (New York, N.Y.) 278, 135-8. PMID: 9311920
4. Yang, YK. et al. (1999) Molecular endocrinology (Baltimore, Md.) 13, 148-55. PMID: 9892020
5. de Rijke, CE. et al. (2005) Biochemical pharmacology 70, 308-16. PMID: 15927146
6. Breit, A. et al. (2006) The Journal of biological chemistry 281, 37447-56. PMID: 17041250
Note For research use only
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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