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  • 100ug
  • 1mg
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Обзор
Каталожный номерHT100011
Описание
Recombinant Human AGRP Protein, C-Fc (HT100011) expressed in Mammalian Cells, spanning Met1-Thr132. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессииMammalian cells
Номер доступаO00253
Длина белкаMet1-Thr132
ПримененияELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
ВидыHomo sapiens (Human)
Характер Recombinant
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса 40.84 kDa
Форма Lyophilized
Буфер хранения Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияAGRP, AGRT, ART, Agouti-related protein
Фон

Agouti-related protein is a ~14 kDa protein. Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptors MC3R and MC4R by precluding agonist-induced signaling, thereby inhibiting cAMP production within the hypothalamus and adrenal gland. Involved in the control of feeding behavior via the central melanocortin system. Has very low activity towards MC5R. Also promotes endocytosis of MC3R and MC4R in an arrestin-dependent mechanism.

1. Bolin, KA. et al. (1999) FEBS letters 451, 125-31. PMID: 10371151
2. Nijenhuis, WA. et al. (2001) Molecular endocrinology (Baltimore, Md.) 15, 164-71. PMID: 11145747
3. Ollmann, MM. et al. (1997) Science (New York, N.Y.) 278, 135-8. PMID: 9311920
4. Yang, YK. et al. (1999) Molecular endocrinology (Baltimore, Md.) 13, 148-55. PMID: 9892020
5. de Rijke, CE. et al. (2005) Biochemical pharmacology 70, 308-16. PMID: 15927146
6. Breit, A. et al. (2006) The Journal of biological chemistry 281, 37447-56. PMID: 17041250
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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