

| Каталожный номер | HC918012 |
|---|---|
| Описание |
Recombinant Human AK4/AK3L1 Protein, N-His (HC918012) expressed in E. coli, spanning Met1-Tyr223. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | P27144 |
| Длина белка | Met1-Tyr223 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 27.43 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | AK3, AK3L1, AK4, Adenylate kinase 3-like, Adenylate kinase 4, mitochondrial, EC:2.7.4.4, EC:2.7.4.6, GTP:AMP phosphotransferase AK4 |
| Фон | Adenylate kinase 4, mitochondrial is a ~25 kDa protein. Broad-specificity mitochondrial nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. Phosphorylates only AMP when using GTP as phosphate donor. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. 1. Liu, R. et al. (2009) Biochemical and biophysical research communications 379, 92-7. PMID: 19073142 2. Panayiotou, C. et al. (2010) The international journal of biochemistry & cell biology 42, 62-9. PMID: 19766732 3. Amiri, M. et al. (2013) The international journal of biochemistry & cell biology 45, 925-31. PMID: 23416111 4. Lanning, NJ. et al. (2014) Cell reports 7, 907-17. PMID: 24767988 |
| Примечание | For research use only |
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