Human AQR Recombinant Protein (N-His) (HC945012)

Name: Human AQR Recombinant Protein (N-His)
Brand: abinScience
SKU: HC945012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HC945012
Description	Recombinant Human AQR Protein, N-His (HC945012) expressed in E. coli, spanning Met1-Ser416. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	O60306
Longueur de protéine	Met1-Ser416
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	50.94 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	AQR, EC:3.6.4.13, IBP160, Intron-binding protein of 160 kDa, KIAA0560, RNA helicase aquarius
Contexte	RNA helicase aquarius is a ~171 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. De, I. et al. (2015) Nature structural & molecular biology 22, 138-44. PMID: 25599396 3. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 4. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 5. Hirose, T. et al. (2006) Molecular cell 23, 673-84. PMID: 16949364
Note	For research use only

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Human AQR Recombinant Protein (N-His).pdf

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