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| カタログ番号 | HC945012 |
|---|---|
| 説明 |
Recombinant Human AQR Protein, N-His (HC945012) expressed in E. coli, spanning Met1-Ser416. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O60306 |
| タンパク質長 | Met1-Ser416 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 50.94 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | AQR, EC:3.6.4.13, IBP160, Intron-binding protein of 160 kDa, KIAA0560, RNA helicase aquarius |
| 背景 | RNA helicase aquarius is a ~171 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. De, I. et al. (2015) Nature structural & molecular biology 22, 138-44. PMID: 25599396 3. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 4. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 5. Hirose, T. et al. (2006) Molecular cell 23, 673-84. PMID: 16949364 |
| 注意事項 | For research use only |
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