

| Каталожный номер | HC945012 |
|---|---|
| Описание |
Recombinant Human AQR Protein, N-His (HC945012) expressed in E. coli, spanning Met1-Ser416. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | O60306 |
| Длина белка | Met1-Ser416 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 50.94 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | AQR, EC:3.6.4.13, IBP160, Intron-binding protein of 160 kDa, KIAA0560, RNA helicase aquarius |
| Фон | RNA helicase aquarius is a ~171 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. De, I. et al. (2015) Nature structural & molecular biology 22, 138-44. PMID: 25599396 3. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 4. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 5. Hirose, T. et al. (2006) Molecular cell 23, 673-84. PMID: 16949364 |
| Примечание | For research use only |
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