Human ASIP Recombinant Protein (N-His-KSI) (HD029012)

Name: Human ASIP Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD029012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HD029012
Description	Recombinant Human ASIP Protein, N-His-KSI (HD029012) expressed in E. coli, spanning His23-Cys132. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P42127
Longueur de protéine	His23-Cys132
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	27.81 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	AGTI, AGTIL, ASIP, ASP, Agouti switch protein, Agouti-signaling protein
Contexte	Agouti-signaling protein is a ~14 kDa protein. Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptor MC1R, thereby playing a role in the regulation of melanogenesis. Binding to MC1R prevents alpha-MSH-induced signaling and inhibits cAMP production, resulting in down-regulation of eumelanogenesis (brown/black pigment) and increased pheomelanin (yellow/red pigment) synthesis. In higher primates, Agouti may affect the quality of hair pigmentation rather than the pattern of pigment deposition. May also play a role in neuroendocrine aspects of melanocortin action. 1. Kempf, E. et al. (2022) Nature metabolism 4, 1697-1712. PMID: 36536132 2. Kanetsky, PA. et al. (2002) American journal of human genetics 70, 770-5. PMID: 11833005
Note	For research use only

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Human ASIP Recombinant Protein (N-His-KSI).pdf

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