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Human ATG9A Recombinant Protein (N-His) (HD739012)

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  • 1mg
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Vista general
Número de catálogoHD739012
Descripción
Recombinant Human ATG9A Protein, N-His (HD739012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoQ7Z3C6
Longitud de proteínaCys155-Pro371
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosAPG9-like 1, APG9L1, ATG9A, Autophagy-related protein 9A, mATG9
Fondo

Autophagy-related protein 9A is a ~94 kDa protein. Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. Also required to supply phosphatidylinositol 4-phosphate to the autophagosome initiation site by recruiting the phosphatidylinositol 4-kinase beta (PI4KB) in a process dependent on ARFIP2, but not ARFIP1. In addition to autophagy, also plays a role in necrotic cell death.

1. Orsi, A. et al. (2012) Molecular biology of the cell 23, 1860-73. PMID: 22456507
2. Karanasios, E. et al. (2016) Nature communications 7, 12420. PMID: 27510922
3. Søreng, K. et al. (2018) EMBO reports 19. PMID: 29437695
4. Antón, Z. et al. (2020) Journal of cell science 133. PMID: 32513819
5. Guardia, CM. et al. (2020) Cell reports 31, 107837. PMID: 32610138
6. Maeda, S. et al. (2020) Nature structural & molecular biology 27, 1194-1201. PMID: 33106659
7. Ravussin, A. et al. (2021) Journal of cell science 134. PMID: 33468622
8. Ghanbarpour, A. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 33850023
9. Young, AR. et al. (2006) Journal of cell science 119, 3888-900. PMID: 16940348
10. Judith, D. et al. (2019) The Journal of cell biology 218, 1634-1652. PMID: 30917996
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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