Human ATL3 Recombinant Protein (N-His) (HD978012)

Name: Human ATL3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD978012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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Обзор

Каталожный номер	HD978012
Описание	Recombinant Human ATL3 Protein, N-His (HD978012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q6DD88
Длина белка	Met1-Asp336
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	AT3, ATL-3, ATL3, Atlastin-3, EC:3.6.5.-
Фон	Atlastin-3 is a ~60 kDa protein. Atlastin-3 (ATL3) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect. Two atlastin-3 on neighboring ER tubules bind GTP and form loose homodimers through the GB1/RHD3-type G domains and 3HB regions. Upon GTP hydrolysis, the 3HB regions tighten, pulling the membranes together to drive their fusion. After fusion, the homodimer disassembles upon release of inorganic phosphate (Pi). 1. Rismanchi, N. et al. (2008) Human molecular genetics 17, 1591-604. PMID: 18270207 2. Hu, J. et al. (2009) Cell 138, 549-61. PMID: 19665976 3. Kornak, U. et al. (2014) Brain : a journal of neurology 137, 683-92. PMID: 24459106 4. Wang, S. et al. (2016) eLife 5. PMID: 27619977 5. Bryce, S. et al. (2023) The Journal of cell biology 222. PMID: 37102997
Примечание	For research use only

Изображения

Ссылки

Даташит

Human ATL3 Recombinant Protein (N-His).pdf

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Formula

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C₁ (Stock Conc.)

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Working Solution

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