Human ATP2C2 Recombinant Protein (N-His) (HF519022)

Name: Human ATP2C2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HF519022
Price: 211 USD
Availability: InStock

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Número de catálogo	HF519022
Descripción	Recombinant Human ATP2C2 Protein, N-His (HF519022) expressed in E. coli, spanning Glu388-Asp576. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	O75185
Longitud de proteína	Glu388-Asp576
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	22.92 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ATP2C2, ATPase 2C2, Ca(2+)/Mn(2+)-ATPase 2C2, Calcium-transporting ATPase type 2C member 2, EC:7.2.2.10, KIAA0703, SPCA2, Secretory pathway Ca(2+)-transporting ATPase type 2
Fondo	Calcium-transporting ATPase type 2C member 2 is a ~103 kDa protein. ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway. Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side. The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state. Induces Ca(2+) influx independently of its ATP-driven pump function. At the basolateral membrane of mammary epithelial cells, interacts with Ca(2+) channel ORAI1 and mediates Ca(2+) entry independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. 1. Xiang, M. et al. (2005) The Journal of biological chemistry 280, 11608-14. PMID: 15677451 2. Vanoevelen, J. et al. (2005) The Journal of biological chemistry 280, 22800-8. PMID: 15831496 3. Dode, L. et al. (2006) The Journal of biological chemistry 281, 3182-9. PMID: 16332677 4. Chen, J. et al. (2019) The Journal of biological chemistry 294, 7878-7891. PMID: 30923126 5. Feng, M. et al. (2010) Cell 143, 84-98. PMID: 20887894 6. Cross, BM. et al. (2013) PloS one 8, e67348. PMID: 23840669
Nota	For research use only

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Datasheet

Human ATP2C2 Recombinant Protein (N-His).pdf

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