Human ATP6V0A1 Recombinant Protein (N-His) (HP002022)

Name: Human ATP6V0A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HP002022
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HP002022
Description	Recombinant Human ATP6V0A1 Protein, N-His (HP002022) expressed in E. coli, spanning Met1-Asn390. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q93050
Longueur de protéine	Met1-Asn390
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	47.53 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ATP6N1, ATP6N1A, ATP6V0A1, Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit, V-ATPase 116 kDa subunit a 1, V-type proton ATPase 116 kDa subunit a 1, VPP1, Vacuolar adenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
Contexte	V-type proton ATPase 116 kDa subunit a 1 is a ~96 kDa protein. Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that transports protons across cellular membranes. V-ATPase is responsible for the acidification of various organelles, such as lysosomes, endosomes, the trans-Golgi network, and secretory granules, including synaptic vesicles. In certain cell types, can be exported to the plasma membrane, where it is involved in the acidification of the extracellular environment. Required for assembly and activity of the vacuolar ATPase. Through its action on compartment acidification, plays an essential role in neuronal development in terms of integrity and connectivity of neurons. 1. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002 2. Aoto, K. et al. (2021) Nature communications 12, 2107. PMID: 33833240 3. Bott, LC. et al. (2021) Brain communications 3, fcab245. PMID: 34909687
Note	For research use only

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Human ATP6V0A1 Recombinant Protein (N-His).pdf

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