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| カタログ番号 | HD776012 |
|---|---|
| 説明 |
Recombinant Human AVPR2 Protein, N-His-KSI (HD776012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P30518 |
| タンパク質長 | Leu2-Ser371 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | ADHR, AVPR V2, AVPR2, Antidiuretic hormone receptor, DIR, DIR3, Renal-type arginine vasopressin receptor, V2R, Vasopressin V2 receptor |
| 背景 | Vasopressin V2 receptor is a ~40 kDa protein. G-protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). AVPR2 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. 1. Birnbaumer, M. et al. (1992) Nature 357, 333-5. PMID: 1534149 2. Böselt, I. et al. (2009) PloS one 4, e5573. PMID: 19440390 3. Wang, L. et al. (2021) Cell research 31, 932-934. PMID: 33664408 4. Zhou, F. et al. (2021) Cell research 31, 929-931. PMID: 33742150 |
| 注意事項 | For research use only |
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