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| カタログ番号 | HD941012 |
|---|---|
| 説明 |
Recombinant Human BCAP31 Protein, N-His (HD941012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P51572 |
| タンパク質長 | Leu168-Leu233 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BAP31, BCAP31, BCR-associated protein 31, Bap31, DXS1357E, Protein CDM, p28 |
| 背景 | B-cell receptor-associated protein 31 is a ~27 kDa protein. Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40. 1. Wakana, Y. et al. (2008) Molecular biology of the cell 19, 1825-36. PMID: 18287538 2. Annaert, WG. et al. (1997) The Journal of cell biology 139, 1397-410. PMID: 9396746 3. Namba, T. (2019) Science advances 5, eaaw1386. PMID: 31206022 4. Nguyen, M. et al. (2000) Molecular and cellular biology 20, 6731-40. PMID: 10958671 |
| 注意事項 | For research use only |
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