

| Numéro de catalogue | HY028012 |
|---|---|
| Description |
Recombinant Human CALCA Protein, N-GST & C-His (HY028012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | P06881 |
| Longueur de protéine | Ala83-Phe119 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 31.97 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | Alpha-type CGRP, CALC1, CALCA, CGRP-I, CGRP1, Calcitonin gene-related peptide 1, Calcitonin gene-related peptide I |
| Contexte | Calcitonin gene-related peptide 1 is a ~13 kDa protein. CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex. 1. Kitamura, K. et al. (1992) Biochemical and biophysical research communications 185, 134-41. PMID: 1318039 2. Josephs, TM. et al. (2021) Science (New York, N.Y.) 372. PMID: 33602864 3. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797 4. Petermann, JB. et al. (1987) The Journal of biological chemistry 262, 542-5. PMID: 3492492 5. Cao, J. et al. (2024) Biochemistry 63, 1089-1096. PMID: 38603770 |
| Note | For research use only |
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