

| Numéro de catalogue | HD918012 |
|---|---|
| Description |
Recombinant Human CAMSAP2 Protein, N-His (HD918012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q08AD1 |
| Longueur de protéine | Asp26-Lys338 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CAMSAP1L1, CAMSAP2, Calmodulin-regulated spectrin-associated protein 1-like protein 1, Calmodulin-regulated spectrin-associated protein 2, KIAA1078 |
| Contexte | Calmodulin-regulated spectrin-associated protein 2 is a ~168 kDa protein. Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In addition, it also reduces the velocity of microtubule polymerization. Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes. 1. Tanaka, N. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 20029-34. PMID: 23169647 2. Jiang, K. et al. (2014) Developmental cell 28, 295-309. PMID: 24486153 3. Hendershott, MC. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 5860-5. PMID: 24706919 4. Wu, J. et al. (2016) Developmental cell 39, 44-60. PMID: 27666745 6. Wei, J. et al. (2017) FEBS letters 591, 2379-2393. PMID: 28726242 |
| Note | For research use only |
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