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| カタログ番号 | HD918012 |
|---|---|
| 説明 |
Recombinant Human CAMSAP2 Protein, N-His (HD918012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q08AD1 |
| タンパク質長 | Asp26-Lys338 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CAMSAP1L1, CAMSAP2, Calmodulin-regulated spectrin-associated protein 1-like protein 1, Calmodulin-regulated spectrin-associated protein 2, KIAA1078 |
| 背景 | Calmodulin-regulated spectrin-associated protein 2 is a ~168 kDa protein. Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In addition, it also reduces the velocity of microtubule polymerization. Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes. 1. Tanaka, N. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 20029-34. PMID: 23169647 2. Jiang, K. et al. (2014) Developmental cell 28, 295-309. PMID: 24486153 3. Hendershott, MC. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 5860-5. PMID: 24706919 4. Wu, J. et al. (2016) Developmental cell 39, 44-60. PMID: 27666745 6. Wei, J. et al. (2017) FEBS letters 591, 2379-2393. PMID: 28726242 |
| 注意事項 | For research use only |
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