

| Numéro de catalogue | HC800011 |
|---|---|
| Description |
Recombinant Human CD158g Protein, C-Fc (HC800011) expressed in Mammalian Cells, spanning His22-His245. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | Mammalian cells |
| Numéro d'accès | Q14953 |
| Longueur de protéine | His22-His245 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 53.07 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CD158 antigen-like family member G, CD158G, CD158g, KIR2DS5, Killer cell immunoglobulin-like receptor 2DS5, NKAT-9, NKAT9, Natural killer-associated transcript 9 |
| Contexte | Killer cell immunoglobulin-like receptor 2DS5 is a ~33 kDa protein. Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity. Able to activate NK cells citotoxicity and cytokine production such as IFNG. Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 represented in this entry. 1. Della Chiesa, M. et al. (2008) European journal of immunology 38, 2284-9. PMID: 18624290 2. Steiner, NK. et al. (2008) Immunogenetics 60, 655-67. PMID: 18682925 3. Blokhuis, JH. et al. (2017) Immunity, inflammation and disease 5, 461-468. PMID: 28685972 4. Steiner, NK. et al. (2014) Human immunology 75, 124-8. PMID: 24269691 |
| Note | For research use only |
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