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Human CD158g Recombinant Protein (C-Fc) (HC800011)

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概要
カタログ番号HC800011
説明
Recombinant Human CD158g Protein, C-Fc (HC800011) expressed in Mammalian Cells, spanning His22-His245. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムMammalian cells
アクセッション番号Q14953
タンパク質長His22-His245
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 53.07 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名CD158 antigen-like family member G, CD158G, CD158g, KIR2DS5, Killer cell immunoglobulin-like receptor 2DS5, NKAT-9, NKAT9, Natural killer-associated transcript 9
背景

Killer cell immunoglobulin-like receptor 2DS5 is a ~33 kDa protein. Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity. Able to activate NK cells citotoxicity and cytokine production such as IFNG. Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 represented in this entry.

1. Della Chiesa, M. et al. (2008) European journal of immunology 38, 2284-9. PMID: 18624290
2. Steiner, NK. et al. (2008) Immunogenetics 60, 655-67. PMID: 18682925
3. Blokhuis, JH. et al. (2017) Immunity, inflammation and disease 5, 461-468. PMID: 28685972
4. Steiner, NK. et al. (2014) Human immunology 75, 124-8. PMID: 24269691
注意事項 For research use only
イメージ
参考文献
Formula
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