Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc) (HV809021)

Name: Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HV809021
Price: 298 USD
Availability: InStock

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1mg

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Vista general

Número de catálogo	HV809021
Descripción	Recombinant Human CD273/PD-L2/PDCD1LG2 Protein, C-Fc (HV809021) expressed in Mammalian Cells, spanning Met1-Thr220. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	Q9BQ51
Longitud de proteína	Met1-Thr220
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	51.24 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	B7-DC, B7DC, Butyrophilin B7-DC, CD273, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, PDL2, Programmed cell death 1 ligand 2, Programmed death ligand 2
Fondo	Programmed cell death 1 ligand 2 is a ~30 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production. 1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527 2. Brown, JA. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 1257-66. PMID: 12538684
Nota	For research use only

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Bioactivity

Immobilized HS870031 Human PD-1 Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind HV809021 Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc), the EC 50 is 324 ng/mL.

Referencias

Datasheet