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Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc) (HV809021)

Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc)
Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc)
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Aperçu
Numéro de catalogueHV809021
Description
Recombinant Human CD273/PD-L2/PDCD1LG2 Protein, C-Fc (HV809021) expressed in Mammalian Cells, spanning Met1-Thr220. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expressionMammalian cells
Numéro d'accèsQ9BQ51
Longueur de protéineMet1-Thr220
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspècesHomo sapiens (Human)
Nature Recombinant
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >90% as determined by SDS-PAGE.
Masse moléculaire prédite 51.24 kDa
Forme Lyophilized
Tampon de stockage Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsB7-DC, B7DC, Butyrophilin B7-DC, CD273, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, PDL2, Programmed cell death 1 ligand 2, Programmed death ligand 2
Contexte

Programmed cell death 1 ligand 2 is a ~30 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.

1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527
2. Brown, JA. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 1257-66. PMID: 12538684
Note For research use only
Images
  • Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc)

    Bioactivity

    Immobilized HS870031 Human PD-1 Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind HV809021 Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc), the EC 50 is 324 ng/mL.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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