Human CHRNA3 Recombinant Protein (N-His) (HB019022)

Name: Human CHRNA3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB019022
Price: 211 USD
Availability: InStock

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Número de catálogo	HB019022
Descripción	Recombinant Human CHRNA3 Protein, N-His (HB019022) expressed in E. coli, spanning Ser32-Leu240. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P32297
Longitud de proteína	Ser32-Leu240
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	26.91 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CHRNA3, NACHRA3, Neuronal acetylcholine receptor subunit alpha-3
Fondo	Neuronal acetylcholine receptor subunit alpha-3 is a ~57 kDa protein. Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA3 forms heteropentameric neuronal acetylcholine receptors with CHRNB2 and CHRNB4, with CHRNA5, and CHRNB3 as accesory subunits. CHRNA3:CHRNB4 being predominant in neurons of the autonomic ganglia, it is known as ganglionic nicotinic receptor. 1. Gharpure, A. et al. (2019) Neuron 104, 501-511.e6. PMID: 31488329 2. Mann, N. et al. (2019) American journal of human genetics 105, 1286-1293. PMID: 31708116 3. Kuryatov, A. et al. (2011) Molecular pharmacology 79, 119-25. PMID: 20881005 4. Wang, F. et al. (1996) The Journal of biological chemistry 271, 17656-65. PMID: 8663494
Nota	For research use only

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Datasheet

Human CHRNA3 Recombinant Protein (N-His).pdf

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