Human CHRNA3 Recombinant Protein (N-His) (HB019022)

Name: Human CHRNA3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB019022
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	HB019022
Описание	Recombinant Human CHRNA3 Protein, N-His (HB019022) expressed in E. coli, spanning Ser32-Leu240. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P32297
Длина белка	Ser32-Leu240
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	26.91 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	CHRNA3, NACHRA3, Neuronal acetylcholine receptor subunit alpha-3
Фон	Neuronal acetylcholine receptor subunit alpha-3 is a ~57 kDa protein. Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA3 forms heteropentameric neuronal acetylcholine receptors with CHRNB2 and CHRNB4, with CHRNA5, and CHRNB3 as accesory subunits. CHRNA3:CHRNB4 being predominant in neurons of the autonomic ganglia, it is known as ganglionic nicotinic receptor. 1. Gharpure, A. et al. (2019) Neuron 104, 501-511.e6. PMID: 31488329 2. Mann, N. et al. (2019) American journal of human genetics 105, 1286-1293. PMID: 31708116 3. Kuryatov, A. et al. (2011) Molecular pharmacology 79, 119-25. PMID: 20881005 4. Wang, F. et al. (1996) The Journal of biological chemistry 271, 17656-65. PMID: 8663494
Примечание	For research use only

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Даташит

Human CHRNA3 Recombinant Protein (N-His).pdf

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