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Human CLCN4 Recombinant Protein (N-His) (HW578012)

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  • 1mg
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Vista general
Número de catálogoHW578012
Descripción
Recombinant Human CLCN4 Protein, N-His (HW578012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoP51793
Longitud de proteínaArg593-Asn760
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosCLCN4, Chloride channel protein 4, Chloride transporter ClC-4, ClC-4, H(+)/Cl(-) exchange transporter 4
Fondo

H(+)/Cl(-) exchange transporter 4 is a ~84 kDa protein. Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters.

1. Zdebik, AA. et al. (2008) The Journal of biological chemistry 283, 4219-27. PMID: 18063579
2. Veeramah, KR. et al. (2013) Epilepsia 54, 1270-81. PMID: 23647072
3. Hu, H. et al. (2016) Molecular psychiatry 21, 133-48. PMID: 25644381
4. Palmer, EE. et al. (2018) Molecular psychiatry 23, 222-230. PMID: 27550844
5. Guzman, RE. et al. (2017) The Journal of biological chemistry 292, 19055-19065. PMID: 28972156
6. Jentsch, TJ. et al. (2018) Physiological reviews 98, 1493-1590. PMID: 29845874
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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