

| Каталожный номер | HW578012 |
|---|---|
| Описание |
Recombinant Human CLCN4 Protein, N-His (HW578012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | P51793 |
| Длина белка | Arg593-Asn760 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | CLCN4, Chloride channel protein 4, Chloride transporter ClC-4, ClC-4, H(+)/Cl(-) exchange transporter 4 |
| Фон | H(+)/Cl(-) exchange transporter 4 is a ~84 kDa protein. Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. 1. Zdebik, AA. et al. (2008) The Journal of biological chemistry 283, 4219-27. PMID: 18063579 2. Veeramah, KR. et al. (2013) Epilepsia 54, 1270-81. PMID: 23647072 3. Hu, H. et al. (2016) Molecular psychiatry 21, 133-48. PMID: 25644381 4. Palmer, EE. et al. (2018) Molecular psychiatry 23, 222-230. PMID: 27550844 5. Guzman, RE. et al. (2017) The Journal of biological chemistry 292, 19055-19065. PMID: 28972156 6. Jentsch, TJ. et al. (2018) Physiological reviews 98, 1493-1590. PMID: 29845874 |
| Примечание | For research use only |
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