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| カタログ番号 | HD391012 |
|---|---|
| 説明 |
Recombinant Human CLIC5 Protein, N-His (HD391012) expressed in E. coli, spanning Pro173-Ser410. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q9NZA1 |
| タンパク質長 | Pro173-Ser410 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 29.16 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CLIC5, Chloride intracellular channel protein 5, EC:1.8.-.-, Glutaredoxin-like oxidoreductase CLIC5 |
| 背景 | Chloride intracellular channel protein 5 is a ~46 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Can insert into membranes and form non-selective ion channels almost equally permeable to Na(+), K(+) and Cl(-). Required for normal hearing. It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti. May play a role in the regulation of transepithelial ion absorption and secretion. 1. Berryman, M. et al. (2004) The Journal of biological chemistry 279, 34794-801. PMID: 15184393 2. Singh, H. et al. (2007) The FEBS journal 274, 6306-16. PMID: 18028448 3. Seco, CZ. et al. (2015) European journal of human genetics : EJHG 23, 189-94. PMID: 24781754 4. Wegner, B. et al. (2010) American journal of physiology. Renal physiology 298, F1492-503. PMID: 20335315 |
| 注意事項 | For research use only |
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