

| Numéro de catalogue | HD900012 |
|---|---|
| Description |
Recombinant Human CPNE1 Protein, N-His (HD900012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q99829 |
| Longueur de protéine | Met1-Ala537 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CPN1, CPNE1, Chromobindin 17, Copine I, Copine-1 |
| Contexte | Copine-1 is a ~59 kDa protein. Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF receptor signaling pathway in a calcium-dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. 1. Tomsig, JL. et al. (2004) The Biochemical journal 378, 1089-94. PMID: 14674885 2. Creutz, CE. et al. (2009) Biochimica et biophysica acta 1788, 1950-61. PMID: 19539605 3. Creutz, CE. et al. (1998) The Journal of biological chemistry 273, 1393-402. PMID: 9430674 4. Park, N. et al. (2012) Molecules and cells 34, 549-54. PMID: 23263657 5. Park, N. et al. (2014) Biochemical and biophysical research communications 454, 228-33. PMID: 25450385 6. Tomsig, JL. et al. (2003) The Journal of biological chemistry 278, 10048-54. PMID: 12522145 7. Ramsey, CS. et al. (2008) Oncogene 27, 3516-26. PMID: 18212740 |
| Note | For research use only |
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