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  • 1mg
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Обзор
Каталожный номерHD964012
Описание
Recombinant Human CREB3 Protein, N-His (HD964012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессииE. coli
Номер доступаO43889
Длина белкаLys145-Thr251
ПримененияELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
ВидыHomo sapiens (Human)
Характер Recombinant
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Форма Lyophilized
Буфер хранения Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияCREB-3, CREB3, Cyclic AMP-responsive element-binding protein 3, LZIP, Leucine zipper protein, Luman, N-terminal Luman, Processed cyclic AMP-responsive element-binding protein 3, Transcription factor LZIP-alpha, Transcriptionally active form, cAMP-responsive element-binding protein 3
Фон

Cyclic AMP-responsive element-binding protein 3 is a ~41 kDa protein. Endoplasmic reticulum (ER)-bound sequence-specific transcription factor that directly binds DNA and activates transcription. Plays a role in the unfolded protein response (UPR), promoting cell survival versus ER stress-induced apoptotic cell death. Also involved in cell proliferation, migration and differentiation, tumor suppression and inflammatory gene expression. Acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Associates with chromatin to the HERPUD1 promoter.

1. Luciano, RL. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 10757-62. PMID: 10984507
2. DenBoer, LM. et al. (2005) Biochemical and biophysical research communications 331, 113-9. PMID: 15845366
3. Liang, G. et al. (2006) Molecular and cellular biology 26, 7999-8010. PMID: 16940180
4. Kang, H. et al. (2009) Molecular endocrinology (Baltimore, Md.) 23, 1746-57. PMID: 19779205
5. Lu, R. et al. (1997) Molecular and cellular biology 17, 5117-26. PMID: 9271389
6. Ko, J. et al. (2004) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18, 890-2. PMID: 15001559
7. Jang, SW. et al. (2007) The Journal of biological chemistry 282, 11092-100. PMID: 17296613
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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